• Dose- and time-dependent effects of triethylene glycol dimethacrylate on the proteome of human THP-1 monocytes 

      Nilsen, Bo Wold; Simon-Santamaria, Jaione; Ørtengren, Ulf Thore; Jensen, Einar; Bruun, Jack-Ansgar; Michelsen, Vibeke Barman; Sørensen, Karen Kristine (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-27)
      Triethylene glycol dimethacrylate (TEGDMA) is commonly used in polymer resinbased dental materials. This study investigated the molecular mechanisms of TEGDMA toxicity by identifying its time- and dose-dependent effects on the proteome of human THP-1 monocytes. The effects of different concentrations (0.07– 5 mM) and exposure times (0–72 h) of TEGDMA on cell viability, proliferation, and morphology ...
    • Effect of cements on fracture resistance of monolithic zirconia crowns 

      Nakamura, Keisuke; Mouhat, Mathieu; Nergård, John Magnus; Lægreid, Solveig Jenssen; Kanno, Taro; Milleding, Percy; Ørtengren, Ulf Thore (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-01-26)
      Objectives - The present study investigated the effect of cements on fracture resistance of monolithic zirconia crowns in relation to their compressive strength.<p> <p>Materials and methods - Four different cements were tested: zinc phosphate cement (ZPC), glass-ionomer cement (GIC), self-adhesive resin-based cement (SRC) and resin-based cement (RC). RC was used in both dual cure mode (RC-D) and ...
    • Fracture resistance of computer-aided design/computer-aided manufacturing-generated composite resin-based molar crowns 

      Harada, A; Nakamura, Keisuke; Kanno, Taro; Inagaki, R.; Ørtengren, Ulf Thore; Niwano, Y.; Sasaki, Keiichi; Egusa, Hiroshi (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-02-16)
      The aim of this study was to investigate whether different fabrication processes, such as the computer-aided design/computer-aided manufacturing (CAD/CAM) system or the manual build-up technique, affect the fracture resistance of composite resin-based crowns. Lava Ultimate (LU), Estenia C&B (EC&B), and lithium disilicate glass-ceramic IPS e.max press (EMP) were used. Four types of molar crowns were ...
    • Fracture resistance of monolithic zirconia molar crowns with reduced thickness 

      Nakamura, Keisuke; Harada, A.; Inagaki, R.; Kanno, Taro; Niwano, Y.; Milleding, Percy; Ørtengren, Ulf Thore (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-01-30)
      Objectives. The purpose of the present study was to analyze the relationship between fracture load of monolithic zirconia crowns and axial/occlusal thickness, and to evaluate the fracture resistance of monolithic zirconia crowns with reduced thickness in comparison with that of monolithic lithium disilicate crowns with regular thickness. Materials and methods. Monolithic zirconia crowns (Lava ...
    • Light-curing units used in dentistry: factors associated with heat development – potential risk for patients 

      Mouhat, Mathieu; Mercer, James; Stangvaltaite, Lina; Ørtengren, Ulf Thore (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-10-01)
      Objectives:<br>To investigate how heat development in the pulp chamber and coronal surface of natural teeth with and without cusps subjected to irradiance using light-emitting diode (LED)–light-curing units (LCUs) is associated with (i) irradiance, (ii) time, (iii) distance, and (iv) radiant exposure.<br> Materials and methods:<br>Three different LED-LCUs were used. Their irradiance was measured ...
    • Opportunities for caries prevention using an ion-releasing coating material: a randomised clinical study 

      Ørtengren, Ulf Thore; Lehrkinder, Anna; Safarloo, Aram; Axelsson, Jasmine; Lingström, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-04)
      Ion-releasing materials (containing fuoride and boron, for example) have shown caries-preventive efects in vitro. The purpose of the present study was to investigate the impact of multi-ion-releasing coating material on pH stabilisation, plaque accumulation and the bacterial composition of dental plaque during a time period of 90 days. The null hypothesis tested here was that the evaluated material ...
    • Photo-irradiated caffeic acid exhibits antimicrobial activity against Streptococcus mutans biofilms via hydroxyl radical formation 

      Nakamura, Keisuke; Shirato, Midori; Kanno, Taro; Lingström, Peter; Ørtengren, Ulf Thore; Niwano, Yoshimi (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-25)
      An antimicrobial technique based on photo-oxidation of caffeic acid (CA) has recently been developed, but its effect on biofilm-forming bacteria is unknown. The present study aimed to evaluate the effect of photo-irradiated CA against Streptococcus mutans (cariogenic bacteria) biofilm as it relates to hydroxyl radical formation. S. mutans biofilms grown on hydroxyapatite disks were immersed in CA ...
    • Suboptimal light curing and direct exposure to water of two contemporary composites: degree of conversion, sorption, solubility, and Knoop hardness 

      Wikant, Aksel; Ørtengren, Ulf Thore; Hakeberg, Magnus; Gedde, Ulf Wiel (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-18)
      The water sorption and solubility of two polymer resin‐based dental composite materials were assessed in order to evaluate the effects of immediate post‐cure water exposure on the water sensitivity of the composites. Each material was tested with two different light curing setups. The radiant exposure of the two curing setups differed by a factor of 5. After exposure to water and subsequent drying, ...